Brooksville is an incorporated city in and the county seat of Hernando County, Florida, United States. It is a suburban city included in the Tampa-St. Petersburg-Clearwater, Florida Metropolitan Statistical Area.
Fort DeSoto, a military fort established about 1840 to give protection to settlers from Native Americans, was located at the northeastern edge of present day Brooksville on Croom Road about one-half mile east of U.S. Highway 41. Fort DeSoto was also a trading post and a regular stop on the Concord Stage Coach Line which ran from Palatka to Tampa. The fort was built on top of a heavy bed of limestone, a fact which they were unaware of at the time, and this made it exceedingly difficult to obtain water, thus causing this location to be abandoned as a community site. As a result, in the early 1840s the population shifted about three miles to the south where a settlement first formed by the Hope and Saxon families became known as Pierceville. About this time, another community about two miles northwest of Pierceville, named Melendez, was formed.