Eustis is a city in Lake County, Florida, United States. The population was 15,106 at the 2000 census.
The people of Eustis, on the east shore of Lake Eustis, took their time deciding on a name. First it was Highlands, then Pendryville, and finally Lake Eustis, itself named about 1825 for General Abraham Eustis. General Eustis, prominent in the Seminole Wars, had skirmished with the Indians on the south shore, near present-day Tavares, Florida. In 1876, A.S. Pendry homesteaded and set out a citrus grove. In 1877 he opened the Ocklawaha Hotel. The post office in the lobby carried the sign Pendryville".Before railroads came in the 1880s, Eustis was a busy port for steamers plying Lakes Harris, Eustis, Dora, and Griffin. In 1883 the "Lake" was dropped and the town became just Eustis. Although the U.S. opened up the area for homesteading in the 1850s, settlement was delayed by the Civil War. Surveying was finally completed in 1875 and settlement began in earnest. Among the earliest settlers was Guilford David "G.D." Clifford, who established a store and began the first mail service for the new settlement. Bertie Clifford was the first baby born before Eustis was incorporated in 1883, and Edith Hutchins the first baby of the newly incorporated town.