Wesley Chapel is a census-designated place (CDP) in Pasco County, Florida, United States. Wesley Chapel is considered part of the Tampa Bay Area metro. The population was 44,092 at the 2010 census. In 2003, some residents of Wesley Chapel started a movement to incorporate the community (including areas not in the official CDP). This "city," which would have been the largest and most populous in Pasco County, never materialized.According to the United States Census Bureau, the CDP has a total area of 6.1 square miles (16 km2), of which 6.1 square miles (16 km2) is land and 0.04 square miles (0.10 km2) (0.49%) is water.Residents choose the area because of its proximity to Interstate 75 and Interstate 275, 25 miles north ofDowntown Tampa, and other major locales. Adjacent to its south is the region of New Tampa, part of incorporated Tampa.