Ashland is a town in Middlesex County, Massachusetts, United States. It is part of the MetroWest region. The population was 16,593 at the 2010 census.
The area now known as Ashland was settled in the early 18th century and inhabited prior to that by the Megunko Native Americans, to which Megunko Hill owes its name. Previously known as "Unionville," Ashland was incorporated in 1846, bearing the name of statesman Henry Clay's Kentucky estate.Decades later, two other rail lines opened stations in Ashland. Along with the Sudbury River, the railroad helped to attract numerous mills to develop a bustling boot and shoe industry.