Oxford is a town in Worcester County, Massachusetts, United States. The population was 13,709 at the2010 census.
Oxford was first settled in 1686 and was officially incorporated in 1713. It was the birthplace of Clara Barton, the first president and founder of the American Red Cross. Oxford was originally settled by Huguenots in two waves, the original settlement having been abandoned after four residents (John Johnson and his three children, Peter, Andrew and Mary) were killed in a violent confrontation with local Native Americans. This event, the Johnson Massacre, is commemorated near the south end of town on Main Street. The remains of the Huguenot Fort (built in 1686) still exist off Huguenot Road.The first town clerk of Oxford was John Town, who also served as selectman and as a church deacon.