Tewksbury is a town in Middlesex County, Massachusetts, United States. The population was 28,961.According to the United States Census Bureau, the town has a total area of 21.1 square miles (55 km2), of which 20.7 square miles (54 km2) is land and 0.3 square miles (0.78 km2), or 1.61%, is water.
Tewksbury was first settled in 1637 and was officially incorporated in 1734 from Billerica. Like Tewksbury Township, New Jersey, it is named after the town of Tewkesbury, England. One of the oldest sections of town is the area around the Shawsheen River. This is where the Shawshin tribe settled, allowing them access to a great food source. Tewksbury was also known for a historic visit by President Andrew Jackson, stopping off at local watering hole, Brown's Tavern.