Toughkenamon is a census-designated place (CDP) in New Garden Township, Chester County, Pennsylvania,United States. The population was 1,492 at the 2010 census.
The area known as Toughkenamon was originally inhabited by Lenape Native Americans who spoke Unami.Thomas and Mary Rowland settled in the valley, near the present village of Toughkenamon, in 1706, being perhaps the first settlers who purchased lands in New Garden Township. They came to the township from old Ashton Township, old Chester County, now in Delaware County.In later centuries Toughkenamon was considered a village. It was an early industrial center due to its strategic location on the old Baltimore Pike between Philadelphia and Washington, D.C., easy access to raw materials such as wood, water and ore. Even today, businesses critical to national wholesale distribution of perishable foods are located in and near Toughkenamon.