Manvel is a city in Brazoria County, Texas, United States. As of the 2010 census the population was 5,179. Iowa Colony is to the west, Pearland is to the north, and Alvin is to the east. Texas State Highway 6 passes through the community, leading 7 miles (11 km) east to Alvin, 37 miles (60 km) east to Galveston, and 20 miles (32 km) northwest to Sugar Land. Texas State Highway 288, a four-lane freeway, runs through the northwest part of Manvel, leading north 20 miles (32 km) to downtown Houston and south 23 miles (37 km) to Angleton, the Brazoria County seat.According to the United States Census Bureau, the city has a total area of 23.6 square miles (61.0 km2), of which 23.5 square miles (60.9 km2) is land and 0.039 square miles (0.1 km2), or 0.12%, is water.