Ludlow is a small town in the Mojave Desert on Interstate 40, located in San Bernardino County, California, United States. The older remains of the ghost town are along historic Route 66.
The town started as a water stop for the Atlantic and Pacific Railroad in 1883. Ore was found in the nearby hills, leading to a boom. From 1906 to 1940 it was the southern railhead for the Tonopah and Tidewater Railroad, operated by the Pacific Coast Borax Company and bringing borax and other mining products from Death Valley and Beatty, Nevada to long distance Santa Fe Railway lines.