Amesbury is a city in Essex County, Massachusetts, located on the left bank of the Merrimack River near its mouth, upstream from Salisbury and across the river from Newburyport and West Newbury. The population was 16,283 at the 2010 census. A former farming and mill town, Amesbury is today largely residential. It is one of the two northernmost towns in Massachusetts (the other being neighboring Salisbury).
In 1637 the first English settler in the Salisbury-Amesbury region, John Bayly, crossed the Merrimack River from the new settlement at Newbury, built a log cabin, and began to clear the land for cultivation. He intended to send to England for his wife and children, but they never did rejoin him. He and his hired man, William Schooler, were arrested shortly for a murder Schooler had committed. The latter was hanged for it. Bayly was acquitted. Given the fishing rights on the river by the subsequent settlement, provided he would sell only to it, he abandoned agriculture for fishing.